Coyote Melon grows in many soils from the edge of the coastal sage scrub through the desert into Nevada and Arizona. A native gourd that develops a large root that supports the rather weird moth Melittia gloriosa. Also found in disturbed, sunny openings, or shade of boulders in creosote woodland; growing with Physalis crassifolia, Encelia farinosa, Sphaeralcea ambigua var. rosacea, Salazaria mexicana, Xylorhiza tortifolia, Atriplex hymenelytra, Nicotiana obtusifolia, Peucephyllum schottii, and Larrea tridentata.
Cucurbita palmata tolerates sand.
Foliage of Cucurbita palmata has color gray and is stressdeciduous.
Communities for Cucurbita palmata:Creosote Bush Scrub, Coastal Sage Scrub and Valley Grassland.